It is uncommon, affecting 1 in 140 pregnant women (0.7%). I have details at home of a support group - I'll post their number later. Obstetric Cholestasis in second pregnancy . The most common symptom is continuous itchiness without a rash. 2002 Mar;109(3):282-8. doi: 10.1111/j.1471-0528.2002.01368.x. Can I open up this thread again? 1 This condition is likely multifactorial in etiology. He also told me that it was almost certain that I would continue to get OC with subsequent pregnancies with the risk of permanent liver damage to me so my dear hubbie had the snip when I was 35 weeks gone. What is obstetric cholestasis? Thanks! Good luck. It also helped with my itching, but apart from that just symtomtic treatment-lots of emmolient cream to stop the skin drying where you've scratched, cool baths and showers, nice cold sheets and a fan in the bedroom all helped me. IF they've done a bile acid test (unlikely, it takes 3 days for teh one lab in Birmingham to do this) 10+ indicates OC. Sorry to ramble on, I’m just a little scared now I’ve reached the final stages. It's on my face and neck, arms, legs, back and bottom. And Urso would take more than a couple of days to have any effect on the itching (if then). My palms are very red and my hands are aching from scratching them so much. The hospital was being perfectly sensible until my consultant turned up and started talking to me like an idiot, but he always does, and by that time I'd been hanging around for seven hours. Is it safe to take ursodeoxycholic acid for so long and does it continue to work for so long? I was diagnosed with Obstetric Cholestasis right towards the end of my 1st pregnany. if it turns out not to be OC, i recommend aqueous cream (available from pharmacies). Although you get all these reassurances from the doctors, it's somehow comforting to chat to other women who've been through the same. Thanks so much for the info, I'll run back up to the hospital now and hope he's not around and I get sensible people instead. Yes, it's only the last few weeks OC is a problem but it means early delivery so I really hope it isn't that. Obstetric cholestasis (OC) is a pregnancy-specific liver condition that typically presents with generalised pruritus in the absence of a rash in the late second trimester or third trimester. The risk if you have obstetric cholestasis may be a little more than this. And if you don't have it they shouldn't be scaring you like this. Obstetric cholestasis (OC) is a pregnancy-specific liver condition that typically presents with generalised pruritus in the absence of a rash in the late second trimester or third trimester. I believe it can even start as early as the second trimester. Intrahepatic cholestasis of pregnancy (ICP) is a poorly understood disease of the late second or third trimester of pregnancy, typically associated with rapid resolution following delivery. Plus since they haven't given me anything for the itching, I just want it to be over while I still have some skin! Has anyone here been diagnosed with Obstetric Cholestasis either in this pregnancy or a previous one?  |  Occasionally it happens in the late second trimester, but it doesn't occur before 20 weeks. I am 33w pregnant of my 3rd baby now. Find out what Mumsnet users thought of Echo by Lloyd’s Pharmacy. Anyway, it wasn't harmful to either me or the baby ("it just happens sometimes during pregnancy" so my gp wasn't very helpful in making the itching stop. I was induced at 37 weeks and had another beautiful girl who does have a condition called craniosynostosis but that was totally unrelated to the OC. For me, the itching started at about 20 weeks and tended to be tops of arms, chest and back. and this website from the US. Wondering if they will bring forwrad the induction? We are now in disaster medicine mode. I’ve been given guidelines as to what I should do the moment the itching starts. . I was put on a drug called ursodeoxycholic acid as soon as I was diagnosed. The signs of obstetric cholestasis usually develop around the end of the second trimester, although the disorder can develop earlier in pregnancy. To use this feature subscribe to Mumsnet Premium - get first access to new features see fewer ads, and support Mumsnet. Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis (OC), is a liver disorder that can develop during pregnancy. I found that Rose's Prickly Heat Powder from Hong Kong worked better than anything else. www - I am really pleased for you. Mutations involving the bile acid transporters may impair maternal excretion and influence transplacental passage of bile acids. If all tests are normal, but you still itching by 28 weeks, insist on a Bile Acid test. So I'm not sure if this is the right place to put this, I've looked all over the forums but couldn't really find anywhere appropriate. If you have medical concerns, please seek medical attention; if you think your problem could be acute, do so immediately. I was induced at 37 weeks and feel it was more painful than going into labour naturally: I had to have an epidural and just made do with gas and air for my second birth. best of luck, hope all goes well for you go and see your doctor as soon as you can to get bile acids checked. Mumsnet hasn't checked the qualifications of anyone posting here. was used to compare pregnancy outcomes of this group with those of the general obstetric population (n = 16,818). I saw the doctor this week, who thought it was a reaction to pregnancy hormones (it's my 2nd pregnancy, but I had nothing like this in the last one). I also had OC, and the main message I got was that once you knew about it you are OK. All experts recommend inducing at 37 weeks if you really do have OC - don't let this crappy consultant fob you off. Cholestasis usually occurs during the third trimester, but it can occur in the second trimester of pregnancy as well. Obstetric cholestasis (OC) is a pregnancy-specific liver condition that typically presents with generalised pruritus in the absence of a rash in the late second trimester or third trimester. In the UK, it affects about 7 in 1000 women (less than 1%). I feel like I have to keep telling them my priority is a healthy baby. Incidentally, the itching started much earlier in this last pregnancy at about 22 weeks. They "think" you have OC! The itching can increase in severity as the pregnancy progresses, and this can interfere with sleep, concentration and mood. I'll see what they say today. Hope you feel better soon. This causes a build-up of bile . Best of luck - I'm sure you'll be absolutely fine. Can it start this early? In ICP, the bile acids do not flow properly and build up in your body instead. Calamine doesn't work, any consultant worth his salt should know that. The risk of a stillbirth in a normal pregnancy is about 1 in 200. I found the ursodeoxycholic acid worked very well and there were no further problems. Do you have questions about creating positive bathroom habits and routines? Women should be counselled about the high recurrence risk of OC in subsequent pregnancies. I’m not sure what the chances are getting it again. 2013 Jun 24;2013(6):CD000493. It is associated with adverse perinatal outcomes including stillbirth, preterm labour and neonatal unit admission. The aim of the present work was to determine maternal and fetal outcomes of intrahepatic cholestasis of pregnancy (ICP) in twin pregnancies. Thanks as well efmach. Many thanks prufrock for all the info. Clipboard, Search History, and several other advanced features are temporarily unavailable. Itching that involves the palms and soles of the feet, is particularly suggestive of OC. Obstetric cholestasis is a multifactorial condition of pregnancy characterised by pruritus in the absence of a skin rash with abnormal liver function tests (LFTs), neither of which has an alternative cause and both of which resolve after birth. Obstetric cholestasis may increase your chance of having a stillbirth. I've just used some spray on that so maybe it'll ease (it's working already, my feet are feeling better) but my hands and arms are still itching and the rash is also still there. Maybe I'm being neurotic but I woke up this morning with a rash on my arms and legs and itching. NLM Obstetric cholestasis is uncommon. susanita Mon 31-Mar-03 15:36:51. It was only after seeing a midwife for a routine appointment who, after seeing me scratch myself furiously, referred me to another midwife who liaises with consultants dealing with OC that I was told that doctors had overlooked abnormal blood results and I had to be induced that day as it was dangerous for the baby – I was 2 days over the due date. Even qualified doctors can't diagnose over the internet, so do bear that in mind when seeking or giving advice. It is also known as obstetric cholestasis (OC) and characterized by pruritus with increased serum bile acids and other liver function tests. I'm going back this morning for monitoring. Heat makes it worse.I've been particularly careful about what I ate yesterday, as some foods seem to make it worse. I am 22wks with baby no.3. Mothers whose family birth origins are India or Pakistan have a slightly higher risk (1-2%). Usually occurring in the last trimester of pregnancy. Have they done LFT's and bile acid tests? I had OC with my first child which started at about 26 weeks. • Pregnant woman in the second half of pregnancy experiencing itch (pruritus) in the absence of a skin rash (other than excoriation) and associated with raised bile acids with or without abnormal liver function tests (raised AST/ALT/GGT) and with no alternative cause and resolving after delivery 3. ICP typically presents after 28 weeks of gestation with pruritus most commonly of the palms of the hands and soles of the feet, and sometimes intractable. Call the OC helpline on 0121 353 0699 to get more advice - they are really lovely. On the positive side, if creams/sprays are making the itching feel better it is unlikely to be OC - nothing stops that itching! 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